Polar Body Emission Requires a RhoA Contractile Ring and Cdc42-Mediated Membrane Protrusion
نویسندگان
چکیده
منابع مشابه
Polar body emission requires a RhoA contractile ring and Cdc42-mediated membrane protrusion.
Vertebrate oocyte maturation is an extreme form of asymmetric cell division, producing a mature egg alongside a diminutive polar body. Critical to this process is the attachment of one spindle pole to the oocyte cortex prior to anaphase. We report here that asymmetric spindle pole attachment and anaphase initiation are required for localized cortical activation of Cdc42, which in turn defines t...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2008
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2008.07.005